The ketogenic diet, which involves high fat and low carbohydrate intake, has been a popular wellness trend for years. However, a recent study published in Science Advances warns about serious health risks from long-term use. Research on mice fed a ketogenic diet for extended periods showed they developed hyperlipidemia, liver dysfunction, and glucose intolerance due to impaired insulin secretion. Medical experts explain that while the diet may offer short-term benefits, prolonged adherence can stress key organs like the liver and pancreas. The liver must work harder to convert fats into ketones, potentially causing fat accumulation. Additionally, high saturated fat intake may elevate cholesterol levels and reduce insulin sensitivity over time. Experts emphasize that safe, long-term keto diets require medical supervision, inclusion of healthy fats, and regular health monitoring. Most effects are reversible if the diet is modified appropriately.
Safe Long-Term Keto Practices and Reversibility of Effects
Medical supervision is essential for safely following a keto diet over extended periods. Dr Bhushan Bhole, Senior Consultant GI Surgery and Liver Transplantation at PSRI Hospital, recommends choosing healthy fats like olive oil, nuts, seeds, and avocados while avoiding processed meats and saturated fats. Periodic reintroduction of complex carbohydrates and fibre-rich foods helps maintain gut health and metabolic balance. Regular monitoring of liver function, lipid profile, and kidney health is crucial for anyone on keto beyond a few months. Most health effects are reversible once the diet includes balanced macronutrients. The liver and pancreas typically return to normal function, though reversing conditions like fatty liver or cholesterol imbalance may require time, exercise, and balanced nutrition.
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