Saralnama
Nails, composed of keratin, protect fingertips and regrow after clipping or injury. Research shows stem cells in the nail bed not only form the nail plate but also trigger digit regeneration by activating the Wnt signaling pathway, which attracts nerves essential for regrowth. Similarly, lizards regenerate lost tails through a complex genetic response involving over 300 genes that coordinate wound healing and tail replacement. Recent studies from IISER Pune reveal that in plants, cell geometry and internal mechanical tension guide root tip regeneration by altering cell shape and division patterns, a process called morphogenesis. This highlights the role of physical cell cues alongside genetic pathways in tissue regeneration, suggesting universal principles in biological shape formation across species. (Updated 23 Aug 2025, 06:04 IST; source: link)