Comedian Amy Schumer recently shared her experience managing perimenopause symptoms through a combination of medications, including Mounjaro, a drug originally designed for type 2 diabetes. In a candid Instagram video, the 43-year-old explained that after struggling with Wegovy years ago, she turned to hormonal support with estrogen and progesterone, along with Mounjaro. She reported improvements in energy, hair fullness, skin quality, and even her interest in intimacy. While Mounjaro is not a hormone therapy, doctors note it may help with perimenopause-related issues indirectly by improving insulin resistance and metabolism. The medication works by mimicking gut hormones that regulate blood sugar and appetite. However, medical experts caution that it is not suitable for everyone and comes with potential side effects. Women considering such treatment should consult healthcare providers to determine the best approach for their individual needs.
How Mounjaro May Help Beyond Weight Loss
Dr Chetna Jain, director of obstetrics and gynaecology at Cloudnine Hospital in Gurgaon, explains that Mounjaro mimics gut hormones to manage blood sugar, appetite, and insulin response. During perimenopause, many women face increased insulin resistance, particularly around the abdomen, due to declining estrogen. By improving how the body processes sugar and reducing inflammation, women may experience better energy, improved sleep, and mood stabilisation. In Schumer's case, combining hormonal support with Mounjaro likely contributed to her feeling better overall. While the drug does not directly affect estrogen levels, its indirect benefits—such as reducing stubborn weight and fatigue—can create a positive ripple effect on overall wellbeing during this transitional phase.
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